A.    Publications – Prof MF Cotton

1.    Nelson A, Maritz J, Giddy J, Cotton MF, et al. HIV testing and antiretroviral therapy initiation at birth: Views from a primary care setting in Khayelitsha. S Afr J HIV Med. 2015;16(1)
2.    Cotton MF, Rabie H: Impact of earlier combination antiretroviral therapy on outcomes in children. Current opinion in HIV and AIDS 2015, 10(1):12-17.
3.    Fisher RG, Smith DM, Murrell B, Slabbert R, Kirby BM, Edson C, Cotton MF, Haubrich RH, Kosakovsky Pond SL, Van Zyl GU: Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure. J Clin Virol 2015, 62:48-53.
4.    Hassan H, Cotton MF, Rabie H: Complicated and Protracted Cryptococcal Disease in HIV-infected Children. Pediatr Infect Dis J 2015, 34(1):62-65.
5.    Mandalakas AM, Kirchner HL, Walzl G, Gie RP, Schaaf HS, Cotton MF, Grewal HM, Hesseling AC: Optimizing the Detection of Recent Tuberculosis Infection in Children in a High TB-HIV Burden Setting. American journal of respiratory and critical care medicine 2015.
6.    Sy SK, Malmberg R, Matsushima A, Asin-Prieto E, Rosenkranz B, Cotton MF, Derendorf H, Innes S: Effect of reducing the paediatric stavudine dose by half: A physiologically-based pharmacokinetic model. Int J Antimicrob Agents 2015.
7.    Frigati, L., Cotton, M., & Rabie, H. (2014). Antiretroviral therapy for the management of HIV in children. South African Medical Journal, 104(12), 898.
8.    Reikie BA, Adams RC, Leligdowicz A, Ho K, Naidoo S, Ruck CE, de Beer C, Preiser W, Cotton MF, Speert DP et al: Altered Innate Immune Development in HIV-Exposed Uninfected Infants. J Acquir Immune Defic Syndr 2014, 66(3):245-255
9.    Walters E, Duvenhage J, Draper HR, Hesseling AC, Van Wyk SS, Cotton MF, Rabie H: Severe manifestations of extrapulmonary tuberculosis in HIV-infected children initiating antiretroviral therapy before 2 years of age. Archives of Disease in Childhood 2014
10.    Bekker A, Schaaf S, Seifart HI, Draper HR, Werely CJ, Cotton MF and Hesseling AC. Pharmacokinetics of Isoniazid in Low-Birth-Weight and Premature Infants, Antimicrob. Agents Chemother. 2014, 58(4):2229.
11.    Innes S, Grobbelaar N, Eley B, Violari A and Cotton MF, Early severe HIV disease precedes early antiretroviral therapy in infants: Are we too late? Journal of the International AIDS Society 2014, 17:18914
12.    Ackermann C, Andronikou S, Laughton B, Kidd M, Dobbels E, Innes S, van Toorn R, Cotton M. White Matter Signal Abnormalities in Children with suspected HIV-Related Neurologic Disease on Early Combination Antiretroviral Therapy. Pediatr Infect Dis J 2014; 33(8):e207-12. PMID 24595047; PMCID: 4153800
13.    Andronikou S, Ackermann C, Laughton B, Cotton MF, Tomazos N, Spottiswood  B, Mauff K, Pettifor JM. Correlating brain volume and callosal thickness with clinical and laboratory indicators of disease severity in children with HIV-related brain disease.Childs Nerv Syst. published online 23 May 2014. DOI 10.1007/s00381-014-2434-3
14.    Cotton MF and Rabie H. Impact of earlier combination antiretroviral therapy on outcomes in children, Curr Opin HIV AIDS 2014, 9:000–000
15.    Gray DM, Workman LJ, Lombard CJ, Jennings T, Innes S, Cotton M, et al, Isoniazid preventive therapy in HIV-infected children on antiretroviral therapy: a pilot study. Int J Tuberc Lung Dis 2014. 18(3):322–327
16.    Cotton M, Cassim H, Pavía-Ruz N, Garges HP. Pharmacokinetics and 48-week Safety and Antiviral Activity of Fosamprenavir/Ritonavir-containing regimens in HIV-infected 4 weeks to 2-year-old children – 48 Week Study Data. Pediatr Infect Dis J 2014;33:57–62
17.    Simania OE, Izua A, Violari A, Cotton MF, van Niekerk N, et al, Effect of HIV-1 exposure and antiretroviral treatment strategies in HIV-infected children on immunogenicity of vaccines during infancy. AIDS 2014, 28:531–541
18.    Cotton MF, Slogrove A and Rabie H. Infections in HIV-exposed Uninfected Children With Focus on Sub-Saharan Africa, The Pediatric Infectious Disease Journal 2014, Volume 33 No 10
19.    Givens N, Ross LL, Lou Y, Perger T, Cotton MF, et al. Pharmacokinetics and 48-week Safety and Antiviral Activity of Fosamprenavir-containing regimens in HIV-infected 2- to 18-year-old children Pediatr Infect Dis J 2014;33:50–56
20.    Naranbhai V, Kim S, Fletcher H, Cotton M, Violari A, et al. The association between the ratio of monocytes: lymphocytes at age 3 months and risk of tuberculosis(TB) in the first two years of life, BMC Medicine 2014, 12:120
21.    de Waal R, Kroon M, Holgate SL, Horn AR, Cotton MF, et al. Nevirapine Concentrations in Preterm and Low Birth Weight HIV-Exposed Infants: Implications for Dosing Recommendations, The Pediatric Infectious Disease Journal. 2014
22.    Edson C, Lenker U, Cotton M, Klinker H, et al. Are lopinavir and efavirenz serum concentrations in HIV-infected children in the therapeutic range in clinical practice? Paediatrics and International Child Health 2014 Vol. 34 No. 2
23.    Frigati L, van der Merwe JL, Harvey J, Rabie H, Theron G, Cotton MF; A retrospective review of group B streptococcal infection in the Metro East area of the Western Cape province: 2010 to 2011 South Afr J Epidemiol Infect 2014;29(1):33-36)
24.    Simani OE, Izua A, Violari A, Cotton M, van Niekerk N, et al. Effect of HIV-1 exposure and antiretroviral treatment strategies in HIV-infected children on immunogenicity of vaccines during infancy AIDS 2014, 28:531–541
25.    Bekker, H. S. Schaaf, H. I. Seifart, H. R. Draper, C. J. Werely, M. F. Cotton and A. C. Hesseling; Pharmacokinetics of Isoniazid in Low-Birth-Weight and Premature Infants Antimicrob. Agents Chemother. 2014, 58(4):2229
26.    Cotton M, Cassim H, Pavía-Ruz N, Garges HP, Perger T, et al. Pharmacokinetics, Safety and Antiviral Activity of Fosamprenavir/Ritonavir-containing Regimens in HIV-infected
Children Aged 4 Weeks to 2 Years—48-week Study Data. Pediatr Infect Dis J 2014, 33:57–62
27.    Fortuny C, Duiculescu D, Cheng K, Garges HP, Cotton M, et al. Pharmacokinetics and 48-week Safety and Antiviral Activity of Fosamprenavir-containing Regimens in HIV-infected 2- to 18-year-old Children; Pediatr Infect Dis J 2014, 33:50–56
28.    Seedat S, Nöthling J, Martin CL, Laughton B, Cotton MF. Maternal post-traumatic stress disorder, depression and alcohol dependence and child behaviour outcomes in mother–child dyads infected with HIV: a longitudinal study; MJ Open 2013; 3:e003638.
29.    Cotton MF, Violari A, Otwombe K, Panchia R, Dobbels E, Rabie H, Josipovic D, Liberty A, Lazarus E, Innes S et al: Early time-limited antiretroviral therapy versus deferred therapy in South African infants infected with HIV: results from the children with HIV early antiretroviral (CHER) randomised trial. The Lancet 2013, 382(9904):1555-1563.
30.    Donald PR, Ahmed A, Burman WJ, Cotton MF, Graham SM, Mendel C, McIlleron H, Mac Kenzie WR, Nachman S, Schaaf HS et al: Requirements for the clinical evaluation of new anti-tuberculosis agents in children. Int J Tuberc Lung Dis 2013, 17(6):794-799.
31.    Fortuny C, Duiculescu D, Cheng K, Garges HP, Cotton M, Tamarirt DP, Ford SL, Wire MB, Givens N, Ross LL et al: Pharmacokinetics and 48 Week Safety and Antiviral Activity of Fosamprenavir-Containing Regimens in HIV-Infected 2 to 18 Year-Old Children. Pediatr Infect Dis J 2013.
32.    Hunt G, Mkhize N, Cotton M, F.: The Mississippi baby? questions on a ‘functional’ cure. In. Edited by Oliviero Td; 2013.
33.    Innes S, Schulte-Kemna E, Cotton MF, Zollner EW, Haubrich R, Klinker H, Sun X, Jain S, Edson C, van Niekerk M et al: Biceps skin-fold thickness may detect and predict early lipoatrophy in HIV-infected children. Pediatr Infect Dis J 2013, 32(6):e254-262.
34.    Walters E, Reichmuth K, Dramowski A, Marais BJ, Cotton MF, Rabie H: Antiretroviral regimens containing a single protease inhibitor increase risk of virologic failure in young HIV-infected children. Pediatr Infect Dis J. 2013 Apr;32(4):361-3.
35.    Pitcher RD, Lombard C, Cotton MF, Beningfield SJ, Zar HJ: Clinical and immunological correlates of chest X-ray abnormalities in HIV-infected South African children with limited access to anti-retroviral therapy. Pediatr Pulmonol. 2013 Aug 22
36.    Kalk E, Slogrove A, Speert DP, Bettinger JA, Cotton MF, Esser M: HIV sero-conversion during late pregnancy – when to retest. Southern African Journal of HIV Medicine 2013, 14(2):90.
37.    Langerak NG, du Toit J, Burger M, Cotton MF, Springer PE, Laughton B: Spastic diplegia in children with HIV encephalopathy: first description of gait and physical status. Developmental medicine and child neurology 2013.
38.    le Roux SM, Cotton MF, Myer L, le Roux DM, Schaaf HS, Lombard CJ, Zar HJ: Safety of long-term isoniazid preventive therapy in children with HIV: a comparison of two dosing schedules. Int J Tuberc Lung Dis 2013, 17(1):26-31.
39.    Madhi SA, Izu A, Violari A, Cotton MF, Panchia R, Dobbels E, Sewraj P, van Niekerk N, Jean-Philippe P, Adrian PV et al: Immunogenicity following the first and second doses of 7-valent pneumococcal conjugate vaccine in HIV-infected and -uninfected infants. Vaccine 2013, 31(5):777-783.
40.    Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC: Detecting tuberculosis infection in HIV-infected children: a study of diagnostic accuracy, confounding and interaction. Pediatr Infect Dis J 2013, 32(3):e111-118.
41.    Nothling J, Martin CL, Laughon BE, Cotton M, F., Seedat S: Maternal post-traumatic stress disorder, depression and alcohol dependence and child behaviour outcomes in mother–child dyads infected with HIV: a longitudinal study. BMJ Open 2013, 3:e003638.
42.    Kalk, E., Slogrove, A., Speert, D.P., Bettinger, J., Cotton, M.F. and Esser, M.HIV seroconversion during late pregnancy – when to retest, S Afr J HIV Med 2013;14(2):90-92
43.    Pitcher RD, Lombard C, Cotton MF, Beningfield SJ, Zar HJ: Clinical and immunological correlates of chest X-ray abnormalities in HIV-infected South African children with limited access to anti-retroviral therapy. Pediatric pulmonology 2013.
44.    Reikie BA, Naidoo S, Ruck CE, Slogrove AL, de Beer C, la Grange H, Adams RC, Ho K, Smolen K, Speert DP et al: Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life. Clinical and vaccine immunology : CVI 2013, 20(1):33-38.
45.    Schaaf HS, Cotton M, F., Boon GPG, Jeena PM: Isoniazid preventive therapy in HIV-infected and -uninfected children (0 – 14 years). S Afr Med J 2013, 103(10):714-715.
46.    Simani OE, Adrian PV, Violari A, Kuwanda L, Otwombe K, Nunes MC, Cotton MF, Madhi SA: Effect of in-utero HIV exposure and antiretroviral treatment strategies on measles susceptibility and immunogenicity of measles vaccine. AIDS 2013, 27(10):1583-1591.
47.    Sy SKB, Innes S, Derendorf H, Cotton MF, Rosenkranz B: Estimation of intracellular concentration of stavudine- triphosphate in HIV-infected children given the reduced dose of 0.5 mg/kg twice daily. Antimicrob Agents Chemother 2013.
48.    Vanden Driessche K, Marais BJ, Wattenberg M, Magis-Escurra C, Reijers M, Tuinman IL, Boeree MJ, van Soolingen D, de Groot R, Cotton MF: The Cough Cylinder: a tool to study measures against airborne spread of (myco-) bacteria. Int J Tuberc Lung Dis 2013, 17(1):46-53.
49.    von Bibra M, Rosenkranz B, Pretorius E, Rabie H, Edson C, Lenker U, Cotton M, Klinker H: Are lopinavir and efavirenz serum concentrations in HIV-infected children in the therapeutic range in clinical practice? Paediatrics and international child health 2013.
50.    Weber HC, Gie RP, Cotton MF: The challenge of chronic lung disease in HIV-infected children and adolescents. J Int AIDS Soc 2013, 16(1).
51.    Zunza M, Mercer GD, Thabane L, Esser M, Cotton MF: Effects of postnatal interventions for the reduction of vertical HIV transmission on infant growth and non-HIV infections: a systematic review. J Int AIDS Soc 2013, 16:18865.
52.    Mandalakas AM, Van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC. Detecting Tuberculosis Infection in HIV-Infected Children: A Study of Diagnostic Accuracy, Confounding and Interaction. Pediatr Infect Dis J 2012
53.    Cotton MF, Marais B, Andersson M, Eley B, Rabie H, Slogrove A, Dramowski A, Schaaf HS and Methar S: Commentary: minimizing the risk of non-vertical, non-sexual HIV infection in children – beyond mother to child transmission. JIAIS 2012, 15:17377. IF 6.245
54.    Slogrove A, Reikie B, Naidoo S, De Beer C, Cotton MF, et al: HIV-exposed infected infants are at increased risk in the first year of life. J Trop Paediatr 2012, 58(6) : 505-508.
55.    Nachega JB, Uthman OA, Anderson J, Pletzer K, Wampold S, Cotton MF, Mills EJ, Ho Y, et al: Adherence to antiretroviral therapy during and after pregancy in low-income, middle-income and high-income countries: a systematic review and meta-analysis. AIDS 2012, 26:2039-2052. IF 6.245
56.    Innes S, Cotton MF, Haubrich R, Conradie MM, et al: High prevalence of Lipoatrophy in pre-pubertal South African children on antiretroviral therapy: a cross-sectional study. BMC Pediatrics 2012; 12 : 1-19
57.    Wiseman CA, Gie RP, Starke JR, Schaaf HS, Donald PR, Cotton MF, Hesseling AC: A proposed comprehensive classification of tuberculosis disease severity in children. Pediatr Infect Dis J 2012, 31(4):347-352.  Cited by 1; IF 3.577
58.    Violari A, Lindsey JC, Hughes MD, Mujuru HA, Barlow-Mosha L, Kamthunzi P, Chi BH, Cotton MF, Moultrie H, Khadse S et al: Nevirapine versus ritonavir-boosted lopinavir for HIV-infected children. N Engl J Med 2012, 366(25):2380-2389. IF 53.298
59.    Laughton B, Cornell M, Grove D, Kidd M, Springer PE, Dobbels E, Rensburg AJ, Violari A, Babiker AG, Madhi SA, Cotton MF et al: Early antiretroviral therapy improves neurodevelopmental outcomes in infants. AIDS 2012. IF 6.245
60.    Kiser JJ, Zhu R, D’Argenio D Z, Cotton MF, Bobat R, McSherry GD, Madhi SA, Carey VJ, Seifart HI, Werely CJ et al: Isoniazid Pharmacokinetics, Pharmacodynamics, and Dosing in South African Infants. Ther Drug Monit 2012. IF 2.491
61.    Holgate SL, Rabie H, Smith P, Cotton MF: Trough Lopinavir Concentrations in Preterm HIV-infected Infants. Pediatr Infect Dis J 2012, 31(6):602-604. IF 3.577
62.    Holgate SL, Bekker A, Rabie H, Cotton MF: Oseltamivir use in low-birth weight infants during the 2009 nH1N1 influenza a outbreak in the Western Cape, South Africa. J Trop Paediatr 2012, 58(2):102-106. IF 1.388
63.    Hesseling AC, Kim S, Madhi S, Nachman S, Schaaf HS, Violari A, Victor TC, McSherry G, Mitchell C, Cotton MF: High prevalence of drug resistance amongst HIV-exposed and -infected children in a tuberculosis prevention trial. Int J Tuberc Lung Dis 2012, 16(2):192-195. IF IF 2.731
64.    Heidari S, Mofenson LM, Hobbs CV, Cotton MF, Marlink R, Katabira E: Unresolved Antiretroviral Treatment Management Issues in HIV-Infected Children. J Acq Immune Def Syndr 2012, 59(2):161-169. IF 4.425
65.    Cuevas LE, Browning R, Bossuyt P, Casenghi M, Cotton MF, Cruz AT, Dodd LE, Drobniewski F, Gale M, Graham SM et al: Evaluation of Tuberculosis Diagnostics in Children: 2. Methodological Issues for Conducting and Reporting Research Evaluations of Tuberculosis Diagnostics for Intrathoracic Tuberculosis in Children. Consensus From an Expert Panel. J infect Dis  2012. Cited by 5; IF 6.410
66.    Cotton MF, Rabie H: Group B streptococcal disease in infants. Lancet 2012. IF 38.278
67.    Bekker A, Preez KD, Schaaf HS, Cotton MF, Hesseling AC: High tuberculosis exposure among neonates in a high tuberculosis and human immunodeficiency virus burden setting. Int J Tuberc Lung Dis 2012. IF 2.731
68.    Boulle A, Thompson ML, Laubscher R, Cotton MF, et.al: Provincial Differences in Infant Deaths in South Africa – An Effect of Antiretroviral Interventions? The SA Journal of HIV Med 2011,
69.    Wiseman CA, Schaaf HS, Cotton MF, Gie RP, Jennings T, Whitelaw A, Roux P, Hesseling AC: Bacteriologically confirmed tuberculosis in HIV-infected infants: disease spectrum and survival. Int J Tuberc Lung Dis 2011, 15(6):770-775. Cited by 7; IF 2.731
70.    van Zyl GU, Rabie H, Nuttall JJ, Cotton MF: It is time to consider third-line options in antiretroviral-experienced paediatric patients? J Int AIDS Soc 2011, 14:55. IF 3.256
71.    Slogrove A, Rabie H, Cotton M: Paediatric Antiretroviral Drug Targets. Infect Disord Drug Targets 2011. Cited by 1
72.    Sharland M, Luck S, Griffiths P, Cotton M: Antiviral therapy of CMV disease in children. Adv Exp Med Biol 2011, 697:243-260. Cited by 1; IF 1.093
73.    Schubert PT, Cotton MF, Wright CA: Cytomorphological patterns of M. bovis BCG and M. tuberculosis on fine needle aspiration biopsies: Does HIV make a difference? Diagn Cytopathol 2011, 39(4):264-269. Cited by 1; IF 1.160
74.    Rabie H, Violari A, Duong T, Madhi SA, Josipovic D, Innes S, Dobbels E, Lazarus E, Panchia R, Babiker AG and Cotton MF: Early antiretroviral treatment reduces risk of bacille Calmette-Guérin immune reconstitution adenitis. Int J Tuberc Lung Dis 2011, 15(9):1194-1200. Cited by 2; IF 2.731
75.    Papasavvas E, Azzoni L, Foulkes A, Violari A, Cotton MF, Pistilli M, Reynolds G, Yin X, Glencross DK, Stevens WS et al: Increased Microbial Translocation in </=180 Days Old Perinatally Human Immunodeficiency Virus-Positive Infants as Compared With Human Immunodeficiency Virus-exposed Uninfected Infants of Similar Age. Pediatr Infect Dis J 2011. Cited by 2; IF 3.577
76.    O’Connell N, Freeman N, Rabie H, Cotton MF: Presumed Cytomegalovirus Retinitis in Human Immunodeficiency Virus Type I-Infected South African Children. Pediatr Infect Dis J 2011. IF 3.577
77.    Mugabo P, Els I, Smith J, Rabie H, Smith P, Mirochnick M, Steyn W, Hall D, Madsen R, Cotton MF: Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention of mother-to-child transmission of HIV-1. S Afr Med J 2011, 101(9):655-658. Cited by 3; IF 2.042
78.    McIlleron H, Ren Y, Nuttall J, Fairlie L, Rabie H, Cotton M, Eley B, Meyers T, Smith PJ, Merry C et al: Lopinavir exposure is insufficient in children given double doses of lopinavir/ritonavir during rifampicin-based treatment for tuberculosis. Antiviral therapy 2011, 16(3):417-421. Cited by 7; IF 3.161
79.    Maritz ER, Kidd M, Cotton MF: Premasticating Food for Weaning African Infants: A Possible Vehicle for Transmission of HIV. Pediatrics 2011. Cited by 1; IF 5.437
80.    Marais BJ, Rabie H, Cotton MF: TB and HIV in children – advances in prevention and management. Paediatr Resp Rev 2011, 12:39-45. Cited by 14; IF 2.197
81.    Madhi SA, Violari A, Klugman KP, Lin G, McIntyre JA, von Gottberg A, Jean-Philippe P, Cotton MF, Adrian P: Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization. Vaccine 2011, 29(40):6994-7001. Cited by 5; IF 3.766
82.    Madhi SA, Nachman S, Violari A, Kim S, Cotton MF, Bobat R, Jean-Philippe P, McSherry G, Mitchell C: Effect of primary isoniazid prophylaxis against tuberculosis in HIV-exposed children. N Eng J Med 2011, 365(1):21-31. Cited by 12; IF 53.298
83.    le Roux DM, Cotton MF, le Roux SM, Whitelaw A, Lombard CJ, Zar HJ: Bacteremia in Human Immunodeficiency Virus-infected Children in Cape Town, South Africa. Pediatr Infect Dis J 2011:1. IF 3.577
84.    Jaspan HB, Myer L, Madhi SA, Violari A, Gibb DM, Stevens WS, Dobbels E, Cotton MF: Utility of clinical parameters to identify HIV infection in infants below ten weeks of age in South Africa: a prospective cohort study. BMC pediatrics 2011, 11(1):104. IF 1.885
85.    Innes S, Cotton MF, Venter F: Why should we still care about the stavudine dose? S Afr JHIV Med 2011(42):14-15.  Cited by 2; IF 0.195
86.    Holgate SL, Bekker A, Rabie H, Cotton MF: Oseltamivir Use in Low-Birth Weight Infants During the 2009 nH1N1 Influenza A Outbreak in the Western Cape, South Africa. J Trop Paediatr 2011. IF 1.388
87.    Heidari S, Mofenson L, Cotton MF, Marlink R, Cahn P, Katabira E: Antiretroviral Drugs for Preventing Mother-to-Child Transmission of HIV: A Review of Potential Effects on HIV-Exposed but Uninfected Children. J Acquir Immune Defic Syndr 2011, 57(4). Cited by 6; IF 4.425
88.    Hainline C, Taliep R, Sorour G, Nachman S, Rabie H, Dobbels E, van Rensburg AJ, Cornell M, Violari A, Madhi SA and Cotton MF: Early Antiretroviral Therapy reduces the incidence of otorrhea in a randomized study of early and deferred antiretroviral therapy: Evidence from the Children with HIV Early Antiretroviral Therapy (CHER) Study. BMC Res Notes 2011, 4:448.
89.    Frigati LJ, Kranzer K, Cotton MF, Schaaf HS, Lombard CJ, Zar HJ: The impact of isoniazid preventive therapy and antiretroviral therapy on tuberculosis in children infected with HIV in a high tuberculosis incidence setting. Thorax 2011. Cited by 4; IF 6.840
90.    Dramowski A, Bekker A, Kirsten G, Marais BJ, Rabie H, Cotton MF: A case of congenital measles during the 2010 South African epidemic. Ann Trop Paediatr 2011, 31(2):185-188. IF 1.388
91.    Zeegers I, Rabie H, Swanevelder S, Edson C, Cotton M, van Toorn R: Attention deficit hyperactivity and oppositional defiance disorder in HIV-infected South African children. J Trop Paediatr 2010, 56(2):97-102. Cited by 3; IF 1.248
92.    Zar HJ, Workman L, le Roux SM, Jennings T, Jele N, Schaaf HS, Barclay-Loggie A, Mulligan C, le Roux DM, Lombard CJ et al: A randomized controlled trial of intermittent compared with daily cotrimoxazole preventive therapy in HIV-infected children. AIDS 2010, 14(24). Cited by 2; IF 6.348
93.    van Zyl GU, Cotton MF, Claassen M, Abrahams C, Preiser W: Surveillance of transmitted resistance to antiretroviral drug classes among young children in the Western Cape Province of South Africa. Pediatr Infect Dis J 2010, 29(4):370-371. IF 3.064
94.    van Toorn R, Schoeman JF, Cotton M, Rabie H: Atypical features of congenital syphilis in an HIV-exposed uninfected neonate. Pediatr Int 2010, 52(2):332-333. IF 0.755
95.    Van der Linden D, Cotton MF, Rabie H, McKerrow N: Fatal Hepatitis B Infection Despite Immunization in an HIV-infected Infant: A Possible Case of Vaccine Failure and Immune Reconstitution Inflammatory Syndrome. J Trop Pediatr 2010. Cited by 1; IF 1.248
96.    Slogrove AL, Kunneke HM, Engelbrecht A, Holgate S, Cotton MF, Rabie H: Evaluating antibiotic use in a secondary level hospital neonatal unit in the Western Cape, South Africa. South Afr J Epidemiol Infect 2010, 25(3):21-25.
97.    Slogrove AL, Cotton MF, Esser MM: Severe infections in HIV-exposed uninfected infants: clinical evidence of immunodeficiency. J Trop Pediatr 2010, 56(2):75-81. Cited by 17; IF 1.248
98.    Rabie H, Lomp A, Goussard P, Nel E, Cotton M: Paradoxical Tuberculosis associated Immune Reconstitution Inflammatory Syndrome Presenting with Chylous Ascites and Chylothorax in a HIV-1 Infected Child. J Trop Pediatr 2010. Cited by 2; IF 1.248
99.    Palumbo P, Lindsey J, Hughes MD, Cotton MF, Bobat R, Meyers T, Bwakura-Dangarembizi M, Chi BH, Musoke P, Kamthunzi P et al: Antiretroviral Treatment for Children with Peripartum Nevirapine Exposure. N Engl J Med 2010, 363:1510-1520. Cited by 49; IF 53.486
100.    Nourse PJ, Cotton MF, Bates WD: Renal manifestations in children co-infected with HIV and disseminated tuberculosis. Pediatr Nephrol 2010, 25(9):1759-1763. Cited by 2; IF 2.183
101.    Nel ED, Rabie H, Goodway J, Cotton MF: A Retrospecive Study of Cryptosporidial Diarrhea in a Region with High HIV Prevalence. J Trop Pediatr 2010. Cited by 1; IF 1.224
102.    Marais BJ, Rabie H, Cotton MF: TB and HIV in children – advances in prevention and management. Paediatr Resp Rev 2010. Cited by 13; IF 2.676
103.    Madhi SA, Adrian P, Cotton MF, McIntyre JA, Jean-Philippe P, Meadows S, Nachman S, Kayhty H, Klugman KP, Violari A: Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants. J Infect Dis 2010, 202(3):355-361. Cited by 10; IF 3.064
104.    Li RJ, Jaspan HB, O’Brien V, Rabie H, Cotton MF, Nattrass N: Positive futures: a qualitative study on the needs of adolescents on antiretroviral therapy in South Africa. AIDS Care 2010, 22(6):751-758. Cited by 3; IF 1.539
105.    Laughton B, Springer P, Grove D, Seedat S, Cornell M, Kidd M, Madhi SA, Cotton MF: Longitudinal development profile of children from low socio-economic circumstances in Cape Town, using the 1996 Griffiths mental development scales. S Afr J Child Health 2010, 4(3):78-83. Cited by 1
106.    Innes S, Schaaf HS, Hoek KG, Rabie H, Cotton M: Unsuspected Fatal Drug-Resistant Tuberculosis in a Closely Monitored Child: A Plea for Improved Source-Case Tracing and Drug Susceptibility Testing. South Afr J Epidemiol Infect 2010, 25(2):30-32.
107.    Hartley C, Pretorius K, Mohamed A, Laughton B, Madhi S, Cotton MF, Steyn B, Seedat S: Maternal postpartum depression and infant social withdrawal among human immunodeficiency virus (HIV) positive mother-infant dyads. Psychol Health Med 2010, 15(3):278-287. Cited by 3
108.    Gray D, Nuttall J, Lombard C, Davies MA, Workman L, Apolles P, Eley B, Cotton M, Zar H: Low rates of hepatotoxicity in HIV-infected children on anti-retroviral therapy with and without isoniazid prophylaxis. J Trop Paediatr 2010, 56(3):159-165. IF 1.248
109.    Eshun-Wilson I, Havers F, Nachega JB, Prozesky HW, Taljaard JJ, Zeier MD, Cotton M, Simon G, Soentjens P: Evaluation of paradoxical TB-associated IRIS with the use of standardized case definitions for resource-limited settings. J Int Assoc Physicians AIDS Care (Chic) 2010, 9(2):104-108. Cited by 9
110.    Nachega JB, Hislop M, Nguyen H, Dowdy DW, Chaisson RE, Regensberg L, Cotton M, Maartens G: Antiretroviral therapy adherence, virologic and immunologic outcomes in adolescents compared with adults in southern Africa. J Acquir Immune Defic Syndr 2009, 51(1):65-71. Cited by 34: IF 4.207
111.    Meintjies G, Rabie H, Wilkinson RJ, Cotton MF: Tuberculosis associated Immune Reconstitution Inflammatory Syndrome and unmasking of tuberculosis by antiretroviral therapy. In: Clinics in Chest Medicine. Volume 30, edn. Philadelphia: Saunders; 2009: 797-810. Cited by 24; IF 2.505
112.    Martinson NA, Moultrie H, van Niekerk R, Barry G, Coovadia A, Cotton M, Violari A, Gray GE, Chaisson RE, McIntyre JA et al: HAART and risk of tuberculosis in HIV-infected South African children: a multi-site retrospective cohort. Int J Tuberc Lung Dis 2009, 13(7):862-867. Cited by 17; IF 2.548
113.    le Roux SM, Cotton MF, Golub JE, le Roux DM, Workman L, Zar HJ: Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules. BMC Med 2009, 7:67. Cited by 9; IF 3.985
114.    Hesseling AC, Johnson LF, Jaspan H, Cotton MF, Whitelaw A, Schaaf HS, Fine PE, Eley BS, Marais BJ, Nuttall J et al: Disseminated bacille Calmette-Guerin disease in HIV-infected South African infants. Bulletin of the World Health Organization 2009, 87(7):505-511. Cited by 25; IF 5.302
115.    Hesseling AC, Cotton MF, Jennings T, Whitelaw A, Johnson LF, Eley B, Roux P, Godfrey-Faussett P, Schaaf HS: High incidence of tuberculosis among HIV-infected infants: evidence from a South African population-based study highlights the need for improved tuberculosis control strategies. Clin Infect Dis 2009, 48(1):108-114. Cited by 68; IF 9.154
116.    Gray TC, Cooke ML, Rabie H, Kidd M, Cotton MF: Pediatric and Adolescent Imported Malaria in Cape Town. Pediatr Infect Dis J 2009, 28(7):644-646. IF 2.854
117.    Gray DM, Zar H, Cotton M: Impact of tuberculosis preventive therapy on tuberculosis and mortality in HIV-infected children. Cochrane Database Syst Rev 2009(1):CD006418.
118.    Gray D, Nuttall J, Lombard C, Davies MA, Workman L, Apolles P, Eley B, Cotton M, Zar H: Low Rates of Hepatotoxicity in HIV-infected Children on Anti-retroviral Therapy with and Without Isoniazid Prophylaxis. J Trop Pediatr 2009. IF 1.224
119.    Dramowski A, Morsheimer MM, Frigati L, Schaaf HS, Rabie H, Sorour G, Cotton MF: Radiology services for children in HIV- and TB-endemic regions: scope for greater collaboration between radiologists and clinicians caring for children. Pediatr Radiol 2009.  IF 1.674
120.    Bourne DE, Thompson M, Brody LL, Cotton M, Draper B, Laubscher R, Abdullah MF, Myers JE: Emergence of a peak in early infant mortality due to HIV/AIDS in South Africa. AIDS 2009, 23(1): 101-106. Cited by 18; IF 6.245
121.    Walters E, Cotton MF, Rabie H, Schaaf HS, Walters LO, Marais BJ: Clinical presentation and outcome of tuberculosis in human immunodeficiency virus infected children on anti-retroviral therapy. BMC Pediatr 2008, 8:12. Cited by 51; IF 1.885
122.    Violari A, Cotton MF, Gibb DM, Babiker AG, Steyn J, Madhi SA, Jean-Philippe P, McIntyre JA: Early antiretroviral therapy and mortality among HIV-infected infants. N Engl J Med 2008, 359(21):2233-2244. Cited by 368: IF 53.298
123.    van Zyl GU, Claassen M, Engelbrecht S, Laten JD, Cotton MF, Theron GB, Preiser W: Zidovudine with nevirapine for the prevention of HIV mother-to-child transmission reduces nevirapine resistance in mothers from the Western Cape, South Africa. J Med Virol 2008, 80(6):942-946. Cited by 15; IF 2.820
124.    Solomons RS, Rabie H, Nel ED and Cotton MF: An overview of hepatitis A at Tygerberg Children’s Hospital. S Afr J Child Health 2008, 2:43-45.  No impact factor
125.    Marais BJ, Esser M, Godwin S, Rabie H, Cotton MF: Poverty and human immunodeficiency virus in children: a view from the Western Cape, South Africa. Ann N Y Acad Sci 2008, 1136:21-27. Cited by 9; IF 2.847
126.    Mak TK, Hesseling AC, Hussey GD and Cotton MF: Making BCG vaccination programmes safer in the HIV era. Lancet 2008, 372(9641):786-787. Cited by 8; IF 38.278
127.    Jaspan HB, Huang LC, Cotton MF, Whitelaw A, Myer L: Bacterial disease and antimicrobial susceptibility patterns in HIV-infected, hospitalized children: a retrospective cohort study. PLoS ONE 2008, 3(9): e3260. Cited by 11; IF 4.092
128.    Hesseling AC, Cotton MF, Jennings T, Whitelaw A, Johnson LF, Eley B, Roux P, Godfrey-Faussett P, Schaaf HS: High Incidence of Tuberculosis among HIV-Infected Infants: Evidence from a South African Population-Based Study Highlights the Need for Improved Tuberculosis Control Strategies. Clin Infect Dis 2008. IF 8.266
129.    Cross Continents Collaboration for Kids (3Cs4kids) Analysis and Writing Committee: Markers for predicting mortality in untreated HIV-infected children in resource-limited settings: a meta-analysis. AIDS 2008, 22:97-105. Cited by 13; IF 5.460
130.    Cotton MF, Wasserman E, Smit J, Whitelaw A, Zar HJ: High incidence of antimicrobial resistant organisms including extended spectrum beta-lactamase producing Enterobacteriaceae and methicillin-resistant Staphylococcus aureus in nasopharyngeal and blood isolates of HIV-infected children from Cape Town, South Africa. BMC Infect Dis 2008, 8:40. Cited by 32; IF 2.536
131.    Cotton MF, Schaaf HS, Lottering G, Weber HL, Coetzee J, Nachman S: Tuberculosis exposure in HIV-exposed infants in a high-prevalence setting. Int J Tuberc Lung Dis 2008, 12(2):225-227. Cited by 23; IF 2.304
132.    Burman WJ, Cotton MF, Gibb DM, Walker AS, Vernon AA, Donald PR: Ensuring the involvement of children in the evaluation of new tuberculosis treatment regimens. PLoS Med 2008, 5(8):e176. Cited by 28; IF 12.185
133.    Arrive E, Kyabayinze DJ, Marquis B, Tumwesigye N, Kieffer MP, Azondekon A, Wemin L, Fassinou P, Newell ML, Leroy V et al: Cohort profile: the paediatric antiretroviral treatment programmes in lower-income countries (KIDS-ART-LINC) collaboration. Int J Epidemiol 2008, 37(3):474-480. Cited by 25; IF 5.838
134.    Abraham DR, Rabie H, Cotton MF: Nitazoxanide for severe cryptosporidial diarrhea in human immunodeficiency virus infected children. Pediatr Infect Dis J 2008, 27(11):1040-1041. Cited by 1; IF 3.176
135.    Zar HJ, Cotton MF, Strauss S, Karpakis J, Hussey G, Schaaf HS, Rabie H, Lombard CJ: Effect of isoniazid prophylaxis on mortality and incidence of tuberculosis in children with HIV: randomised controlled trial. BMJ 2007, 334(7585):136. Cited by 105; IF 9.723
136.    Sneag DB, Schaaf HS, Cotton MF, Zar HJ: Failure of chemoprophylaxis with standard antituberculosis agents in child contacts of multidrug-resistant tuberculosis cases. Pediatr Infect Dis J 2007, 26(12):1142-1146. Cited by 24: IF 3.086
137.    Rabie H, de Boer A, van den Bos S, Cotton MF, Kling S, Goussard P: Children with Human Immunodeficiency Virus Infection Admitted to a Paediatric Intensive Care Unit in South Africa. J Trop Pediatr 2007. Cited by 20; IF 1.018
138.    Marais BJ, Esser M, Godwin S, Rabie H, Cotton M: Poverty and HIV in children a view from the Western Cape, South Africa. Ann N Y Acad Sci 2007. IF 1.731
139.    Lesch A, Swartz L, Kagee A, Moodley K, Kafaar Z, Myer L, Cotton M: Paediatric HIV/AIDS disclosure: towards a developmental and process-oriented approach. AIDS Care 2007, 19(6):811-816. Cited by 33; IF 0.672
140.    Hesseling AC, Cotton MF, Marais BJ, Gie RP, Schaaf HS, Beyers N, Fine PE, Abrams EJ, Godfrey-Faussett P, Kuhn L: BCG and HIV reconsidered: moving the research agenda forward. Vaccine 2007, 25(36):6565-6568. Cited 18; IF 3.37
141.    Arrive E, Kyabayinze DJ, Marquis B, Tumwesigye N, Kieffer MP, Azondekon A, Wemin L, Fassinou P, Newell ML, Leroy V et al: Cohort Profile: The Paediatric Antiretroviral Treatment Programmes in Lower-Income Countries (KIDS-ART-LINC) Collaboration. Int J Epidemiol 2007. Cited by 26; IF 5.151
142.    van Kooten Niekerk NK, Knies MM, Howard J, Rabie H, Zeier M, van Rensburg A, Frans N, Schaaf HS, Fatti G, Little F and Cotton MF: The first 5 years of the family clinic for HIV at Tygerberg Hospital: family demographics, survival of children and early impact of antiretroviral therapy. J Trop Pediatr 2006, 52(1):3-11. Cited by 30; IF 0.592
143.    Myer L, Moodley K, Hendricks F, Cotton M: Healthcare providers’ perspectives on discussing HIV status with infected children. J Trop Paediatr  2006, 52(4):293-295. Cited by 29; IF 0.592
144.    Moodley K, Myer L, Michaels D, Cotton M: Paediatric HIV disclosure in South Africa — caregivers’ perspectives on discussing HIV with infected children. S Afr Med J 2006, 96(3):201-204. Cited by 23; IF 1.230
145.    Madide A, Rabie H, Cotton MF: Virological Response without CD4 recovery. A case of disappearing soldiers – can basic science help? S Afr J HIV Med 2006(24):45-47.
146.    Hesseling AC, Rabie H, Marais BJ, Manders M, Lips M, Schaaf HS, Gie RP, Cotton MF, van Helden PD, Warren RM et al: Bacille Calmette-Guerin vaccine-induced disease in HIV-infected and HIV-uninfected children. Clin Infect Dis 2006, 42(4):548-558. Cited by 105; IF 6.186
147.    de Waal N, Rabie H, Bester R, Cotton MF: Mass needle stick injury in children from the Western cape. J Trop Pediatr 2006, 52(3):192-196. Cited by 7; IF 0.592
148.    Claassen M, van Zyl GU, Korsman SN, Smit L, Cotton MF, Preiser W: Pitfalls with rapid HIV antibody testing in HIV-infected children in the Western Cape, South Africa. J Clin Virol 2006, 37(1):68-71. Cited by 20; IF 2.630
149.    Ijpma FF, Beekhuis D, Cotton MF, Pieper CH, Kimpen JL, van den Hoogen BG, van Doornum GJ, Osterhaus DM: Human metapneumovirus infection in hospital referred South African children. J Med Virol 2004, 73(3):486-493. Cited by 56: IF 2.779
150.    Hiemstra R, Rabie H, Schaaf HS, Eley B, Cameron N, Mehtar S, Janse van Rensburg A and Cotton MF: Unexplained HIV-1 infection in children–documenting cases and assessing for possible risk factors. S Afr Med J 2004, 94(3):188-193. Cited by 24; IF 1.107
151.    Hesseling AC, Schaaf HS, Victor T, Beyers N, Marais BJ, Cotton MF, Wiid I, Gie RP, Van Helden P, Warren RM: Resistant Mycobacterium bovis Bacillus Calmette-Guerin Disease : Implications for Management of Bacillus Calmette-Guerin Disease in Human Immunodeficiency Virus-Infected Children. Pediatr Infect Dis J 2004, 23(5):476-479. Cited by 33; IF 2.735
152.    Marais B, Cotton M: Occupational exposure to human immunodeficiency virus in pediatricians: a previously undescribed high risk group. Pediatr Infect Dis J 2003, 22(4):382-383. Cited by2; IF 2.262
153.    Hesseling AC, Schaaf HS, Hanekom WA, Beyers N, Cotton MF, Gie RP, Marais BJ, van Helden P, Warren RM: Danish bacille Calmette-Guerin vaccine-induced disease in human immunodeficiency virus-infected children. Clin Infect Dis 2003, 37(9):1226-1233. Cited by 80; IF 5.393
154.    Hesseling AC, Marais BJ, Cotton MF: A child with neurobrucellosis. Ann Trop Paediatr 2003, 23(2):145-148. Cited by 7; IF 0.704
155.    Saczek KB, Schaaf HS, Voss M, Cotton MF, Moore SW: Diagnostic dilemmas in abdominal tuberculosis in children. Pediatr Surg Int 2001, 17(2-3):111-115. Cited by 19
156.    Roux W, Pieper C, Cotton M: Thrombocytopoenia as marker for HIV exposure in the neonate. J Trop Pediatr 2001, 47(4):208-210.  Cited by 7; IF 1.388
157.    Rabie H, Pieper CH, Robson B, Cotton MF: Postnatal zidovudine in prevention of vertical HIV-1 transmission in a service setting. J Trop Pediatr 2001, 47(4):215-219. Cited by 3; IF 1.388
158.    Uys R, Cotton MF, Wessels G, Hesseling PB, Bester R, Janse van Rensburg E: Viral isolates during febrile neutropaenia in children with cancer. J Trop Pediatr 2000, 46(1):21-24. Cited by 8; IF 1.388
159.    Schaaf HS, Gie RP, van Rie A, Seifart HI, van Helden PD, Cotton MF: Second episode of tuberculosis in an HIV-infected child: relapse or reinfection? J Infect 2000, 41(1):100-103. Cited by 10
160.    Roux P, Henley L, Cotton M, Eley B: Burden and cost of inpatient care for HIV-positive paediatric patients–status in the Cape Town metropole during the second week of March 1999. Paediatric HIV Census Group. S Afr Med J 2000, 90(10):1008-1011. Cited by 7
161.    Regensberg L, Pead C, Mahumapelo J, Cotton M: Prevention of vertical transmission of human immunodeficiency type 1 virus in a managed care setting. S Afr Med J 2000, 90(11):1093-1094.
162.    Pijnenburg MW, Cotton MF: Monotherapy in an era of combination therapy: is there a benefit? Experience in HIV-1-infected symptomatic South African children. Ann Trop Paediatr 2000, 20(3):185-192. Cited by 3; IF 1.388
163.    Orth H, Engelbrecht S, Cotton MF, Robson BA, Smith TL, Schaaf HS, Leibrandt B, Dobbels E, van Rensburg EJ: HIV transmission between two siblings in Africa. AIDS 2000, 14(7):896-897. Cited by 11
164.    du Plessis JK, Muller JB, Poolman M, Viljoen K, Barnes JM, Cotton MF: Awareness of HIV infection among pregnant women attending the Elsies River Antenatal Clinic. S Afr Med J 2000, 90(7):693-696. Cited by 1
165.    Cotton MF, Wasserman E, Pieper CH, Theron DC, van Tubbergh D, Campbell G, Fang FC, Barnes J: Invasive disease due to extended spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal unit: the possible role of cockroaches. J Hosp Infect 2000, 44(1):13-17. Cited by 61
166.    Schaaf HS, Geldenduys A, Gie RP, Cotton MF: Culture-positive tuberculosis in human immunodeficiency virus type 1-infected children. Pediatr Infect Dis J 1998, 17(7):599-604. Cited by 49
167.    Cotton MF, Ikle DN, Rapaport EL, Marschner S, Tseng PO, Kurrle R, Finkel TH: Apoptosis of CD4+ and CD8+ T cells isolated immediately ex vivo correlates with disease severity in human immunodeficiency virus type 1 infection. Pediatr Res 1997, 42(5):656-664. Cited by 29
168.    Donald PR, Cotton MF, Hendricks MK, Schaaf HS, de Villiers JN, Willemse TE: Pediatric meningitis in the Western Cape Province of South Africa. J Trop Pediatr 1996, 42(5):256-261. Cited by 24; IF 1.388
169.    Finkel TH, Tudor-Williams G, Banda NK, Cotton MF, Curiel T, Monks C, Baba TW, Ruprecht RM, Kupfer A: Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat Med 1995, 1(2):129-134. Cited by 722
170.    Cotton MF: Telephone calls to an infectious diseases fellow. Pediatrics 1995, 95(5):753-754. Cited by 16
171.    Nyquist AC, Rotbart HA, Cotton M, Robinson C, Weinberg A, Hayward AR, Berens RL, Levin MJ: Acyclovir-resistant neonatal herpes simplex virus infection of the larynx. J Pediatr 1994, 124(6):967-971. Cited by 26
172.    Cotton MF, Reiley T, Robinson CC, Pedneault L, Alfieri C, Simoes EA: Acute aqueductal stenosis in a patient with Epstein-Barr virus infectious mononucleosis. Pediatr Infect Dis J 1994, 13(3):224-227. Cited by 15
173.    Gunders AF, Cotton MF, Nel E, Hendriks M, Ebrecht K, Hahne H, Redecker R, Shaw ML, V d Walt J, Williams A: Prevalence and intensity of intestinal worm infections in daycare attenders in urban and peri-urban settings in greater Cape Town. S Afr J Epidemiol Infect 1993, 8:48-51.
174.    Cotton MF, Donald PR, Schoeman JF, Van Zyl LE, Aalbers C, Lombard CJ: Raised intracranial pressure, the syndrome of inappropriate antidiuretic hormone secretion, and arginine vasopressin in tuberculous meningitis. Childs Nerv Syst 1993, 9(1):10-15; discussion 15-16. Cited by 10
175.    Abzug MJ, Cotton MF: Severe chickenpox after intranasal use of corticosteroids. J Pediatr 1993, 123(4):577-579. Cited by 50
176.    Cotton MF, Burger PJ, Bodenstein WJ: Bacteraemia in children in the south-western Cape. A hospital-based survey. S Afr Med J 1992, 81(2):87-90. Cited by 25
177.    Donald PR, Schoeman JF, Cotton MF, van Zyl LE: Cerebrospinal fluid investigations in tuberculous meningitis. Ann Trop Paediatr 1991, 11(3):241-246. Cited by 24; IF 1.388
178.    Cotton MF, Hartzenberg B, Donald PR, Burger PJ: Ventriculoperitoneal shunt infections in children. A 6-year study. S Afr Med J 1991, 79(3):139-142. Cited by 8
179.    Cotton MF, Donald PR, Schoeman JF, Aalbers C, Van Zyl LE, Lombard C: Plasma arginine vasopressin and the syndrome of inappropriate antidiuretic hormone secretion in tuberculous meningitis. Pediatr Infect Dis J 1991, 10(11):837-842. Cited by 19
180.    Cotton MF, Donald PR, Aalbers C: Arginine vasopressin concentrations in the cerebrospinal fluid of children. Childs Nerv Syst 1991, 7(7):399-401.
181.    Heney C, Berkowitz F, Baise T, Cotton M, Khoosal M, Vally S, Barriere R, Saunders J, Koornhof HJ: Spread of non-typable multiply resistant Haemophilus influenzae in a South African hospital. Eur J Clin Microbiol Infect Dis 1990, 9(1):24-29. Cited by 7
182.    Muller PD, Cotton MF: Telephone calls to a paediatric department. S Afr Med J 1989, 75(9):454.
183.    Cotton MF, Berkowitz FE, Berkowitz Z, Becker PJ, Heney C: Nosocomial infections in black South African children. Pediatr Infect Dis J 1989, 8(10):676-683. Cited by 17
184.    Cotton MF, Rothberg AD: Methylphenidate v. placebo–a randomised double-blind crossover study in children with the attention deficit disorder. S Afr Med J 1988, 74(6):268-271. Cited by 5
185.    Cotton MF, Berkowitz FE, Ransome OJ: Candidal suppurative thrombophlebitis in a premature infant. Am J Dis Child 1988, 142(3):254-255. Cited by 2
186.    Berkowitz FE, Cotton MF: Endotracheal aspiration for the bacteriological diagnosis of nosocomial- and measles-associated pneumonia. Ann Trop Paediatr 1988, 8(4):217-221. Cited by 6; IF 1.388

B.    Editorials / Opinion Pieces

1.    Lynne M Mofenson and Mark F Cotton. The challenges of success: adolescents with perinatal HIV infection. JIAIS 2013, 16:18650
2.    Cotton MF, Rabie H, van Zyl GU: Another milestone in minimizing risks to mothers exposed to single-dose nevirapine for prevention of vertical transmission of HIV-1 to infants: what next? Clin Infect Dis 2010, 50(6):909-911. Cited by 1; IF 8.186
3.    Cotton MF, Rabie H, van Zyl GU: Antiretroviral therapy in children with tuberculosis: progress toward defining the issues. J Infect Dis 2010, 201(8):1113-1114. IF 6.288
4.    Hesseling AC, Cotton MF, Fordham von Reyn C, Graham SM, Gie RP, Hussey GD: Consensus statement on the revised World Health Organization recommendations for BCG vaccination in HIV-infected infants: Submitted on behalf of the BCG Working Group, Child Lung Health Section, International Union Against Tuberculosis and Lung Disease, 38th Union World Conference on Lung Health, Cape Town, 8-12 November 2007. Int J Tuberc Lung Dis 2008, 12(12):1376-1379. Cited by 40; IF 2.304
5.    Meyers T, Moultrie H, Naidoo K, Cotton M, Eley B, Sherman G: Challenges to pediatric HIV care and treatment in South Africa. J Infect Dis 2007, 196 Suppl 3:S474-481. Cited by 51; IF 6.035
6.    Marais BJ, Graham SM, Cotton MF, Beyers N: Diagnostic and management challenges for childhood tuberculosis in the era of HIV. J Infect Dis 2007, 196 Suppl 1:S76-85. Cited by 88; IF 6.035
7.    Cotton MF: Antiretroviral therapy in children-increased benefit from increased complexity. S Afr Med J 2000, 90(10):985-988. Cited by 1

C.    Scientific letters (peer reviewed)

1.    Abrahams D, Rabie H and Cotton MF. Nitazoxanide for HIV-infected children with cryptosporidial diarrhea. Pediatr Infect Dis J 2008; 27 (11): 1040-1
2.    Hesseling AC, Cotton MF, Marais BJ, Gie RP, Schaaf HS, Beyers N, Fine PEM, Abrams Ej, Godfrey-Faussett P, Kuhn L. BCG and HIV reconsidered: Moving the research agenda forward. J Intern Society for Vaccine 2007; 25: 8: 6565-6568. Cited by 21
3.    Shipton S, Cotton MF, Wessels G, Wasserman E. Endocarditis due to extended spectrum beta-lactamase-producing extended spectrum Klebsiella pneumonia. S Afr Med J 2001; 91: 321.
4.    Cotton MF, Pieper C, Wasserman E, Theron D. Necrotising enterocolitis as an infectious disease: evidence from an outbreak of invasive disease due to extended spectrum beta-lactamase-producing extended spectrum Klebsiella pneumoniae in a nursery. S Afr Med J 2001; 91: 133-135. Cited by 2
5.    Pijnenberg M, Cotton MF. Necrotizing fasciitis in an HIV-1-infected infant. S Afr Med J 2001; 91: 500-501. Cited by 3
6.    Weber HC, Cotton MF.   Invasive group A streptococcal infections after chicken pox – new in South Africa. S Afr Med J 2001; 91: 1044-1045. Cited by 3
7.    Niehaus DJ, Knowles JA, van Kradenberg J, du Toit W, Kaminer D, Seedat S, Daniels W, Cotton M, Brink P, Beyers AD et al: D8/17 in obsessive-compulsive disorder and trichotillomania. S Afr Med J 1999, 89(7):755-756. Cited by 23
8.    Cotton MF, Hayton G. Dental abscesses as a cause of “unexplained” recurrent fever in a 9-year-old boy. S Afr Med J 1999; 89: 841-842.
9.    Weber H, Gie R, Cotton MF, Annandale C, Kling S and Loock J. Upper airway obstruction in a HIV-infected child with acute Epstein-Barr virus infection.  J Trop Paediatr 1999; 45: 119 – 120. 1 citation
10.    Finkel TH, Monks C, Casella C, Cotton MF, Banda NK, Kupfer A, Ikle D. HIV turnover and T Cell death. Nature Medicine 1995; 1: 386-387.
11.    Cotton MF, Shahak E, Muller GJ, Heyns L, Kalis NN, Aalbers C: Syndrome of inappropriate antidiuretic hormone secretion, an unusual complication of an elapid snakebite. S Afr Med J 1991, 79(12):735-736.
12.    Cotton MF, Ransome OJ: Oral ketoconazole and flucytosine for neonatal systemic candidiasis. S Afr Med J 1989, 75(8):388-389. Cited by 2

D.    Journal letters (peer reviewed)

1.    Cotton MF, Darby C, Ballot DE. Neonatal apnoea due to proprietary medicines -still a problem. S Afr Med J 1988; 73:134.
2.    Cotton MF, Berkowitz FE, Ransome OJ. Suppurative candidal thrombophlebitis in a premature infant. Am J Dis Child 1988; 142: 254-255.
3.    Muller PD, Cotton MF, Telephone calls to a paediatric department.   S Afr Med J 1989; 75:454.
4.    Cotton MF, Rothberg AR. Methylphenidate in children with the attention deficit disorder. S Afr Med J 1989; 75:302.
5.    Cotton MF, Shachak E, Muller GJ, Kalis N. SIADH, an unusual complication of snakebite. S Afr Med J 1991; 79:735-736.
6.    Esser M, Cotton MF, Bouic P. Immunologic status of children with Kawasaki syndrome.  S Afr Med J 1992; 81:229-230.
7.    Cotton MF, et al. SIADH in tuberculous meningitis.  Paediatr Infect Dis J 1992; 11:1070-1071.
8.    Abzug MJ, Cotton MF, Corticosteroid therapy and severe chickenpox. J Paediatr 1994; 125: 331.
9.    Hussey G, Fransman D, McGillivray G, Reynolds L, Jacobs M, Power D, Burgess J, Eley B, Woods D, Coetzee N, Anthony J, Maartens G, Schaaf S, Cotton M, Theron G. The mother to child HIV transmission debate.  S Afr Med J 1999; 89:103-104.
10.    Beyer N, Cotton MF, Donald PR et al. The mother to child HIV transmission debate.  S Afr Med J 1999; 89:104-105.
11.    Van Zyl GU, Cotton MF, Janse v Rensburg E. Registry: unusual HIV transmission in children under the age of 10 years.  S Afr Med J 2000; 90:1064-1065. Cited by 3
12.    Karim SSA, Coovadia, J, Adhikhari M, Hussy G and Cotton M. Vertical HIV transmission in South Africa: translating research into policy and practice.  Lancet 2002; 359: 992-3
13.    Abrams AL, Opiyu N, Cotton MF, Crowley S, Okebe J, Wisonge CS: Supporting registration of child-focused clinical trials in Africa: The Child Strategy project. S Afr Med J 2011, 101(11):804. IF 2.042
14.    Marais BJ, Hesseling AC, Cotton MF: Poverty and tuberculosis: is it truly a simple inverse linear correlation? Eur Respir J 2009, 33(4):943-944. Cited by 1; IF 5.527
15.    Abdool Karim S, Abdool Karim Q, Adhikari M, Cassol S, Chersich M, Cooper P, Coovadia A, Coovadia H, Cotton M, Coutsoudis A et al: Vertical HIV transmission in South Africa: translating research into policy and practice. Lancet 2002, 359(9311):992-993. Cited by 27; IF 15.397

E.     Review articles (peer reviewed)

1.    Cotton MF, Cassella C, Rapaport EL, Tseng P-O, Marschner S and Finkel TH. Apoptosis in HIV-1 infection.   Behring Inst. Mitt. 1996; 97: 1 – 12.
2.    Voss M, Cotton MF. Mechanisms and clinical implications of apoptosis. Hosp Med 1999; 59: 924 – 930.
3.    Cotton, MF. Antiretroviral therapy in children – increased benefit from increased complexity.  S Afr Med J 2000; 90: 985-988.
4.    Cotton MF. Immunizations in HIV-infected children.  S Afr J of CME 2001; 19: 399-401.
5.    Cotton MF. Antiretroviral therapy: more about pharmacokinetics in infants and children.  S Afr J of CME 2001; 19: 742-744.
6.    Zar HJ, Cotton MF. Nosocomial pneumonia in Pediatric patients.  Paediatr Drugs 2002; 4: 73-83.
7.    Cotton MF, Schaaf HS, Hesseling AC and Madhi SA. HIV and childhood tuberculosis: the way forward.  Int J Tuberc Lung Dis 2004; 8:675-682. Cited by 22
8.    Cotton MF, Rabie H, Marais BJ, Van Toorn R, Nel ED.   Common opportunistic infections in HIV infected infants and children. Part 2 – non-respiratory infections.  S Afr Family Pract 2007; 49(2): 40-45. Cited by 1
9.    Cotton MF, Innes S, Jaspan H, Madide A, Rabie H.  Management of upper respiratory tract infections in children.  S Afr Family Pract 2008; 50 (2): 6-12.
10.    Bliss SJ, O’Brien KL, Janoff EN, Cotton MF, Musoke P, Coovadia H, Levine OS: The evidence for using conjugate vaccines to protect HIV-infected children against pneumococcal disease. Lancet Infect Dis 2008, 8(1):67-80. Cited by 60; IF 13.165
11.    Cotton MF, Schaaf HS, Hesseling AC, Madhi SA: HIV and childhood tuberculosis: the way forward. Int J Tuberc Lung Dis 2004, 8(5):675-682. Cited by 22; IF 1.484

F.    Non peer reviewed articles

1.    Cotton MF, Zeier M, Schaaf HS, Dhansay S, O Brien V et al. The Family Clinic at Tygerberg Hospital: the first year.  AIDS Bulletin 1998; 7: 30-31.
2.    Cotton MF. Scuttling towards the post antibiotic era.  Tygerland 2000.
3.    Cotton MF. HIV infection in children and neonates: diagnosis and management. Modern Medicine 2000; 25: 27-38.
4.    Cotton MF. HIV infection in children and neonates: antiretroviral therapy.  Modern Medicine 2000; 25: 24-36.
5.    Schaaf HS, Cotton MF, De Villiers G, Donald PR. Clinical insights into the interaction of childhood tuberculosis and HIV in the Western Cape.  S Afr J of HIV Med 2000; 1: 33-35
6.    Cotton MF. The evaluation of fever in neonates, infants and children – a personal viewpoint.  M.A.N. Epistola 2001; 10: 11-12
7.    Cotton MF. The varicella zoster vaccine.  S Afr J of CME 2003; 21: 6: 314-317
8.     Schaaf HS, Cotton MF. Current Childhood Immunizations.  SA Family Pract 2003; 45: 9: 25-31.
9.    Cotton MF, Montfrans JM, Rabie H, Schaaf HS, Hesseling AC, Shipton SE, Victor T. An HIV-infected infant with bacille Calmete-Guérin disease, recurrent and multidrug-resistant tuberculosis  complicated by acute cor pulmonale and hepatitis while on antiretroviral therapy.  SAfr J of HIV Med 2007; 49-49-52.  Cited by 1
10.    Rabie H, Cotton MF, De Boer A, Van den Bos S, Kling S, Goussard P. Children with human immunodeficiency virus infection admitted to a paediatric intensive care unit in South Africa. JTrop Paediatr 2007. Cited by 20
11.    Cotton MF, Rabie H, Marais BJ, Van Toorn R, Nourse P, Nel ED, Goussard P, Seller N, Important HIV-associated conditions in HIV-infected infants and children.  S Afr Family Pract 2007; 49(4):19-23. Cited by 2
12.    Cotton MF, Marais BJ, Graham SM, Beyers N.  Diagnostic and management challenges for childhood tuberculosis in the era of HIV. J of Infectious Diseases 2007; 196: S76- S85 Cited by 70
13.    Dramowsky A, Finlayson H, Marais BJ, Rabie H, Du Preez M, Malek E, Kruger M, Cotton MF: Spots of bother. In: FIDSSA Quarterly. vol. 1; 2010.

G.    Books Chapters

1.    Cotton MF, Kroon SM and Rabie H: HIV in pregnancy: diagnostic and therapeutic implications for the newborn, ERS Monogr 2014; 66: 71–83.
2.    Smit L, Dramaowsky A, Clarke K, Clayton J, Scherer A, Slogrove A, Musvosvi H, Rifkin M, Cotton M, F.: Breaking the cycle: challenges and solutions in HIV policy. In: Protecting childhood in the AIDS pandemic: finding solutions that work. edn. Edited by Heymann J, Sherr L, Kidnan R. Oxford: Oxford University Press; 2012.
3.    Meyers T, Jaspan H, Rabie H, Cotton MF: Principles of Pediatric Antiretroviral Therapy. In: From the Ground Up: Building Comprehensive HIV/AIDS Care Programs in Resource-Limited Settings. Volume 2, edn. Edited by Richard G. Marlink M, Sara J. Teitelman M: Elizabeth Glaser Pediatric AIDS Foundation; 2009: 863-884.
4.    Fowler MG, Handelsman E, Cotton MF.   Pediatric HIV Infection:  Epidemiology, Treatment and Complications in the United States and Internationally.  In: Sexually Transmitted Diseases 4th Edition 2008, 1694-1712
5.    Breastfeeding in Hospitals. In: Handbook of HIV Medicine. 1st edn. Edited by Wilson D, Naidoo S, Bekker L-G, Cotton M, Maartens G. Cape Town: Oxford University Press. Southern Africa; 2002: 304-310. Cited by 26
6.    Paediatric ART Handbook of HIV Medicine
7.    TB co-infection Handbook of HIV Medicine
8.    Approach to the HIV-infected child Handbook of HIV Medicine
9.    Cotton MF, Schaaf HS, Rabie H, Marais BJ: Tuberculosis, in Coovadia’s Paediatrics 6th edn. Cape Town: in Manual of HIV Care Oxford University Press Southern Africa; 2009. IF 3.474
10.    Finkel TH, Cotton MF, Banda NK. Apoptosis as a mechanism of CD4 T cell death in HIV       infection. In: Apoptosis in AIDS and Cancer, LD Tomei, Ed. 1995

H.    Book Editor

1.    Wilson D, Cotton MF, Bekker LG, Naidoo S, Meyers TM and Maartens G (editors). Manual of HIV care in Southern Africa. 3nd ed, Oxford. University Press of Southern Africa, 2012
2.    Wilson D, Cotton MF, Bekker LG, Naidoo S, Meyers TM and Maartens G (editors). Manual of HIV care in Southern Africa. 2nd ed, Oxford. University Press of Southern Africa, December 2008
3.    Wilson D, Bekker LG, Cotton MF, Naidoo S and Maartens G (editors). Manual of HIV care in Southern Africa. Oxford. University Press of Southern Africa, August 2002

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